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Editor-in-chief
Maria Stella Graziani

Deputy Director
Martina Zaninotto

Associate Editors
Ferruccio Ceriotti
Davide Giavarina
Bruna Lo Sasso
Giampaolo Merlini
Martina Montagnana
Andrea Mosca
Paola Pezzati
Rossella Tomaiuolo
Matteo Vidali

EIC Assistant
Francesco Busardò

International Advisory Board Khosrow Adeli Canada
Sergio Bernardini Italy
Marcello Ciaccio Italy
Eleftherios Diamandis Canada
Philippe Gillery France
Kjell Grankvist Sweden
Hans Jacobs The Netherlands
Eric Kilpatrick UK
Magdalena Krintus Poland
Giuseppe Lippi Italy
Mario Plebani Italy
Sverre Sandberg Norway
Ana-Maria Simundic Croatia
Tommaso Trenti Italy
Cas Weykamp The Netherlands
Maria Willrich USA
Paul Yip Canada


Publisher
Biomedia srl
Via L. Temolo 4, 20126 Milano

Responsible Editor
Giuseppe Agosta

Editorial Secretary
Chiara Riva
Biomedia srl
Via L. Temolo 4, 20126 Milano
Tel. 0245498282
email: biochimica.clinica@sibioc.it

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ISSN print: 0393 – 0564
ISSN digital: 0392- 7091



BC: Articoli scritti da G. Marzotto

Un utile riscontro occasionale di variante emoglobinica
Useful occasional report of a haemoglobin variant.
<p>HbA1c is a marker used for diagnosis and management of diabetes. The clinical case described here describes a patient with Impaired Fasting Glucose who requires the measurement of HbA1c in order to define his metabolic status. The capillary electrophoresis (CE) method used for the HbA1c measurement was unable to return a result for HbA1c because of an atypical pattern which required further investigations. The presence of haemoglobin variants can interfere analytically with HbA1c measurements; also abnormalities in erythrocyte turnover can affect the clinical interpretation of HbA1c values. Therefore, it is important to recognize the presence of a haemoglobin variant, to evaluate whether the result returned from the CE instrument is compatible with the patient&rsquo;s situation.<br />This case demonstrates the importance of implementing safety barriers to prevent errors arising from situations that, although already described and well known, may go unnoticed by the laboratory staff.</p>
Biochimica Clinica ; 46(2) e8-e10
Caso Clinico - Case Report