You don't have or don't remember the password! Click Here
Editor-in-chief
Maria Stella Graziani
Deputy Director
Martina Zaninotto
Associate Editors
Ferruccio Ceriotti
Davide Giavarina
Bruna Lo Sasso
Giampaolo Merlini
Martina Montagnana
Andrea Mosca
Paola Pezzati
Rossella Tomaiuolo
Matteo Vidali
EIC Assistant
Francesco Busardò
International Advisory Board
Khosrow Adeli Canada
Sergio Bernardini Italy
Marcello Ciaccio Italy
Eleftherios Diamandis Canada
Philippe Gillery France
Kjell Grankvist Sweden
Hans Jacobs The Netherlands
Eric Kilpatrick UK
Magdalena Krintus Poland
Giuseppe Lippi Italy
Mario Plebani Italy
Sverre Sandberg Norway
Ana-Maria Simundic Croatia
Tommaso Trenti Italy
Cas Weykamp The Netherlands
Maria Willrich USA
Paul Yip Canada
Publisher
Biomedia srl
Via L. Temolo 4, 20126 Milano
Responsible Editor
Giuseppe Agosta
Editorial Secretary
Chiara Riva
Biomedia srl
Via L. Temolo 4, 20126 Milano
Tel. 0245498282
email: biochimica.clinica@sibioc.it
--------------------
ISSN print: 0393 – 0564
ISSN digital: 0392- 7091
BC: Articoli scritti da N. N. Fantini
Una diagnosi in laboratorio
A case of atypical celiac disease with hematological involvement
<p>We report a case of a pregnant 39 year-old woman (22th week) with leuco-granulocitopenia, iron-deficiency anemia and a slight elevation of transaminases, lasting for several years. The origin of these biochemical alterations was unclear. Assuming a possible autoimmune condition, she underwent a hematological counselling in order to verify the presence of an immunological disorder. Anti-nuclear antibodies resulted negative with a citoplasmic filamentous fluorescence suggestive of anti-smooth muscle antibodies (ASMA). On a suitable substrate for ASMA detection, a reticulin-like fluorescence was observed, inducing to investigate for the presence of celiac disease (CD). CD diagnosis requires both the biochemical tests and duodenal biopsy; however, because of the pregnancy only the serum panel was performed (serum IgA, anti-tissue transglutaminase IgA, anti-endomisium IgA). As the tests were all positive, clinicians decided to start the gluten free diet with an improvement of the hematological and biochemical parameters. The patient gave birth to a healthy newborn.</p>
Biochimica Clinica ; 42(1) e08-e011 Casi clinici - Case report
Gentile utente, le ricordiamo che l'accesso alla rivista è riservato ai soci SIBioC in regola con la quota associativa.
Per accedere alla pagina richiesta è necessario inserire il suo nome utente e la password nella sezione "AREA SOCI".
A disposizione per ulteriori informazioni.
La Segreteria SIBioC
Dear User, please note that access to the Journal is for SIBioC members who have renewed their membership fee.
To access the requested page you need to enter username and password in "Area Soci".
At your disposal for further information.
SIBioC Secretariat