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Maria Stella Graziani

Deputy Director
Martina Zaninotto

Associate Editors
Ferruccio Ceriotti
Davide Giavarina
Bruna Lo Sasso
Giampaolo Merlini
Martina Montagnana
Andrea Mosca
Paola Pezzati
Rossella Tomaiuolo
Matteo Vidali

EIC Assistant
Francesco Busardò

International Advisory Board Khosrow Adeli Canada
Sergio Bernardini Italy
Marcello Ciaccio Italy
Eleftherios Diamandis Canada
Philippe Gillery France
Kjell Grankvist Sweden
Hans Jacobs The Netherlands
Eric Kilpatrick UK
Magdalena Krintus Poland
Giuseppe Lippi Italy
Mario Plebani Italy
Sverre Sandberg Norway
Ana-Maria Simundic Croatia
Tommaso Trenti Italy
Cas Weykamp The Netherlands
Maria Willrich USA
Paul Yip Canada

Biomedia srl
Via L. Temolo 4, 20126 Milano

Responsible Editor
Giuseppe Agosta

Editorial Secretary
Chiara Riva
Biomedia srl
Via L. Temolo 4, 20126 Milano
Tel. 0245498282


ISSN print: 0393 – 0564
ISSN digital: 0392- 7091

BC: Articoli scritti da M. D'amora

Utilizzo dei droni per il trasporto di campioni biologici e possibile impiego nella medicina di laboratorio: il progetto PHILOTEA
M. D'amora  | 
Biochimica Clinica ; 44(1) 100-102
Lettere all'Editore - Letters to the Editor
La catena di custodia: problematiche generali ed esperienza nella Azienda Sanitaria Locale Napoli 1 Centro
The chain of custody: general issues and the experience of the Azienda Sanitaria Locale of Naples (Italy)
<p>The toxicology laboratories were created at the end of 1996 within the city area of Naples (Italy) and, so far, have gained an important experience. Their tasks are to monitor drug abuse, the use of metadone and buprenorphine and the diagnosis and monitoring of alcoholism through the screening of urine and serum samples. From this long-lasting experience, we realized that one of the main critical concern of this activity is the implementation and the maintenance of the custody chain, that is especially needed in the presence of forensic issues. The aim of this paper is to analyze the Italian national and regional laws and administrative indications on this topic. We dedicated a particular interest to the rules established by the Regione Campania, where the laboratory is situated. After considering that a high percentage of samples non-conformities were due to the lack of a proper chain of custody (i.e. 66.7%), we adopted a specific procedure based on the use of a dedicated kit containing both the tubes for a safe sample collection and the related documents. A large amount of time was dedicated to illustrate and diffuse the procedure to the nurses and the other personnel working mainly in the First Aid centers of the Azienda Sanitaria Locale of Naples. The collected data show that the percentage of the unsuitable samples decreased to 38% at the end of the year 2017 when the information and training courses succeeded in involving all the dedicated personnel. We plan to revise periodically the procedures and reinforce the message to further optimize the results</p>
Biochimica Clinica ; 43(1) 067-075
Opinioni - Opinions
Diagnostica di laboratorio del rischio nefrolitiasico
Laboratory diagnostics of the nephrolithasic risk.
<p>Laboratory diagnostics of the nephrolithasic risk. The urinary metabolic study is carried out for the evaluation of patients at the first episode of lithiasis but mainly for the monitoring of patients on therapy in order to prevent lithiasis recurrences. Following the indication of the general practitioner or of the nephrologist, our laboratory performs the analysis of both daily and first morning urine to extrapolate the tendency (relative supra-saturation) to form the most common urinary calculi (calcium oxalate, mono calcium phosphate acid, uric acid). In this paper we review the role of the different ions and urinary components in favoring or inhibiting stone formation. Then, we present the whole workflow for the characterization of the tendency of kidney stones formation, from the instructions to the patient for the collection of urines to the interpretative report. Regarding the analytical issues, we briefly present the methods, not commercially available, developed in our center that can be adapted to common biochemical analyzers allowing a complete characterization of the lithiasic tendency without the use of more specialized instrumentation.</p>
Biochimica Clinica ; 42(4) 327-334
Opinioni - Opinions