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Editor-in-chief
Maria Stella Graziani

Deputy Director
Martina Zaninotto

Associate Editors
Ferruccio Ceriotti
Davide Giavarina
Bruna Lo Sasso
Giampaolo Merlini
Martina Montagnana
Andrea Mosca
Paola Pezzati
Rossella Tomaiuolo
Matteo Vidali

EIC Assistant
Francesco Busardò

International Advisory Board Khosrow Adeli Canada
Sergio Bernardini Italy
Marcello Ciaccio Italy
Eleftherios Diamandis Canada
Philippe Gillery France
Kjell Grankvist Sweden
Hans Jacobs The Netherlands
Eric Kilpatrick UK
Magdalena Krintus Poland
Giuseppe Lippi Italy
Mario Plebani Italy
Sverre Sandberg Norway
Ana-Maria Simundic Croatia
Tommaso Trenti Italy
Cas Weykamp The Netherlands
Maria Willrich USA
Paul Yip Canada


Publisher
Biomedia srl
Via L. Temolo 4, 20126 Milano

Responsible Editor
Giuseppe Agosta

Editorial Secretary
Chiara Riva
Biomedia srl
Via L. Temolo 4, 20126 Milano
Tel. 0245498282
email: biochimica.clinica@sibioc.it

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ISSN print: 0393 – 0564
ISSN digital: 0392- 7091



BC: Articoli scritti da M.A. Burgio

Evaluation of the cardiovascular risk in patients undergoing major non-cardiac surgery: role of cardiac-specific biomarkers
Evaluation of the cardiovascular risk in patients undergoing major non-cardiac surgery: role of cardiac-specific biomarkers
<p>Cardiovascular risk evaluation in patients undergoing major non-cardiac surgery: role of cardiac-specific biomarkers.</p><p>Joint document of the Italian Societies of Clinical Biochemistry: European Ligand Assay Society, Sezione Italiana (ELAS), Societ&agrave; Italiana di Biochimica Clinica e Biologia Molecolare Clinica (SIBioC), Societ&agrave; Italiana di Patologia Clinica e Medicina di Laboratorio (SIPMeL) Patients undergoing major surgery have a substantial risk of cardiovascular events during the perioperative period.</p><p>Despite the introduction of several risk scores based on medical history, classical risk factors and non-invasive cardiac tests, the possibility to predict cardiovascular events in patients undergoing non-cardiac surgery remains limited. The cardiac-specific biomarkers natriuretic peptides (NPs) and cardiac troponins (cTn) have been proposed as additional tools for risk prediction in the peri-operative period. This Consensus Document aims to discuss the value of preoperative levels and perioperative changes in cardiac-specific biomarkers to predict adverse outcomes in patients undergoing major non-cardiac surgery. Based on several prospective observational studies and 6 meta-analyses, some guidelines recommended the measurement of NPs to refine perioperative cardiac risk estimation in patients undergoing noncardiac surgery. More recently, several studies reported a higher mortality in surgical patients presenting an elevation in high-sensitivity cTnT and cTnI, especially in elderly patients or those with comorbidities. This evidence should be considered in future international guidelines on the evaluation of perioperative risk in patients undergoing major noncardiac surgery.</p>
Biochimica Clinica ; 46(3) 255-267
Documenti SIBioC - SIBioC Documents
 
Questionario conoscitivo sull'Esame Chimico Morfologico delle Urine in Italia a cura del Gruppo Interdisciplinare Laboratorio e Clinica dell’Apparato Urinario
Results of the survey on chemical and morphological examination of urine in Italy issued by the Italian Interdisciplinary Urinalysis Group
R. Ravasio  |  MA. Burgio  |  F. Balboni  |  F. Manoni  | 
<p>Introduction: the Italian Interdisciplinary Urinalysis Group (GIAU) is a study group aimed to harmonize the standard chemical and morphological urine examination in Italy. The aim of this paper is to present the results of a survey recently released. The survey has been prepared to evaluate the state of the art of the routine standard urine examination in Italy after the issuing by GIAU of the recommendations related to the pre-analytical, analytical and post-analytical phases of the Urine Chemical Morphological Examination (ECMU).<br />Methods: the questionnaire (47 questions) was made available through the web-based Survey Monkey platform to the members of the two Italian Laboratory Medicine scientific societies (SIBioC and SIPMel).<br />Results: 553 replies were collected. Regarding the pre-analytical phase, the most critical issue is the use of a monitored (time and temperature) sample transportation to the clinical laboratory only by a small percentage of the laboratories (30%). More than 80% of the laboratories recommends the collection of the mid-stream urine. Regarding the analytical phase, the majority of the participants utilizes dedicated automated analyzers for urine sediment. Only 15.5% of the participants includes the albumin to creatinine ratio in the standard urine examination.<br />Discussion: the results of the survey give a picture of the state of art of the standard urine examination in Italy. From the comparison with the GIAU previous surveys, it can be concluded that the urinalysis practice in Italy is nowadays more compliant to the indications of the available recommendations and that a general improvement of this laboratory test is observed. Some unsatisfactory answers have been collected for a number of issues, so the role of the GIAU is and will remain fundamental to guide all the laboratory professionals who operate in this laboratory medicine field, towards further advancements.</p>
Biochimica Clinica ; 45(3) 256-266
Contributi Scientifici - Scientific Papers