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Editor-in-chief
Maria Stella Graziani

Deputy Director
Martina Zaninotto

Associate Editors
Ferruccio Ceriotti
Davide Giavarina
Bruna Lo Sasso
Giampaolo Merlini
Martina Montagnana
Andrea Mosca
Paola Pezzati
Rossella Tomaiuolo
Matteo Vidali

EIC Assistant
Francesco Busardò

International Advisory Board Khosrow Adeli Canada
Sergio Bernardini Italy
Marcello Ciaccio Italy
Eleftherios Diamandis Canada
Philippe Gillery France
Kjell Grankvist Sweden
Hans Jacobs The Netherlands
Eric Kilpatrick UK
Magdalena Krintus Poland
Giuseppe Lippi Italy
Mario Plebani Italy
Sverre Sandberg Norway
Ana-Maria Simundic Croatia
Tommaso Trenti Italy
Cas Weykamp The Netherlands
Maria Willrich USA
Paul Yip Canada

Publisher
Biomedia srl
Via L. Temolo 4, 20126 Milano

Responsible Editor
Giuseppe Agosta

Editorial Secretary
Chiara Riva
Biomedia srl
Via L. Temolo 4, 20126 Milano
Tel. 0245498282
email: biochimica.clinica@sibioc.it

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ISSN print: 0393 – 0564
ISSN digital: 0392- 7091

BC: Articoli scritti da A. Apuzzo

Diagnostica di laboratorio del rischio nefrolitiasico
Laboratory diagnostics of the nephrolithasic risk.
G. Cangiano \| E. Di Maina \| G. Buccino \| A. Errico \| P. Improta \| A. Latte \| M. Caputo \| R. Rossano \| A. Apuzzo \| A. K. Saenger \| C. Polito \| F. Nuzzi \| M. D'amora \| A. Tufano \| A. Sarappa \|
<p>Laboratory diagnostics of the nephrolithasic risk. The urinary metabolic study is carried out for the evaluation of patients at the first episode of lithiasis but mainly for the monitoring of patients on therapy in order to prevent lithiasis recurrences. Following the indication of the general practitioner or of the nephrologist, our laboratory performs the analysis of both daily and first morning urine to extrapolate the tendency (relative supra-saturation) to form the most common urinary calculi (calcium oxalate, mono calcium phosphate acid, uric acid). In this paper we review the role of the different ions and urinary components in favoring or inhibiting stone formation. Then, we present the whole workflow for the characterization of the tendency of kidney stones formation, from the instructions to the patient for the collection of urines to the interpretative report. Regarding the analytical issues, we briefly present the methods, not commercially available, developed in our center that can be adapted to common biochemical analyzers allowing a complete characterization of the lithiasic tendency without the use of more specialized instrumentation.</p>
Biochimica Clinica ; 42(4) 327-334 Opinioni - Opinions